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Introducing OmniSeq INSIGHTSM

OmniSeq INSIGHTSM is a comprehensive genomic and immune profiling test that is clinically and analytically validated for all solid tumors. OmniSeq INSIGHTSM interrogates the full exonic coding region of 523 genes by next generation sequencing for mutations, select copy number alterations, and fusions/splice variants including genes associated with homologous recombination repair deficiency (HRR/HRD), microsatellite instability (MSI) and tumor mutational burden (TMB), expression of 64 immune genes, and PD-L1 by immunohistochemistry (IHC). The test informs treatment decisions, including targeted and immunotherapy options to which the patient may be more likely to respond, clinical trials, and mechanisms of decreased response and resistance to therapies based on the individual genomic and immune profile for each patient’s tumor.

Cancer Type
All Solid Tumors

Specimen Type
FFPE

Specimen Requirements
Preferred: FFPE Block
Alternate: 20 unstained slides

Typical Turnaround Time
10 days or less from receipt of specimen and complete order

Order OmniSeq INSIGHTSM

OmniSeq INSIGHTSM Gene List

OmniSeq INSIGHTSM Technical Information 

Expanded Insight = Increased Options

Marker-Driven FDA Approved Therapy Associations

Markers with NCCN Therapeutic Guidance Evidence

Markers with Clinical Trial Associations

Industry-guided content for a comprehensive view of cancer-related fusion genes, detecting common and novel fusions.

Detect Fusions Missed By DNA-seq

Effectively Match Patients to the Right Trial
MOLECULAR + IMMUNE PROFILING = MORE PATIENT OPTIONS

PROFILING THE ACTIONABLE CANCER GENOME

Comprehensive Trial Matching Across the Actionable Cancer Genome for Solid Tumors

Genes

Trials

Expertly Curated Clinical Trial Matching Assessing Biomarker-Based Eligibility Criteria, Multi-Arm Study Designs and Treatment Context Assertions

PROFILING THE TUMOR MICROENVIRONMENT

Increase Clinical Trial Options by Targeting Biomarkers Involved in the Adaptive Immune System

Genes

Trials

Understanding the Anti-Cancer Immune Response is Critical to Adapt Therapies to the Cancer Phenotype.

OmniSeq Delivers the Only Test Matching Trials to Tumor-Immune Mechanisms and Low-Expressing Genes Involved in Inflammatory Signaling 

Key Clinical Report Features

Solid Tumor Genomic and Immune Profiling

Results at-a-glance

  • Detected mutations, rearrangements (fusions/splice variants), copy number changes (gain/loss), TMB, MSI, and PD-L1 (IHC)
  • RNA-based detection of fusions and splice variants
  • Highly expressed immunotherapy targets for clinical trial identification
  • Pertinent negatives for the tested tumor type
  • Matched therapies, resistance associations and geographically focused clinical trials
  • Potential cancer-associated germline variants flagged

Therapy Considerations

At-a-glance and detailed marker clinical significance and efficacy evidence for matched FDA-approved targeted therapies, immunotherapies, and clinical trials.

Personalized Marker Details

Comprehensive annotation of clinically relevant markers for precision medicine selection and support of molecular tumor boards

Trust a test provider ISO13485:2016 CERTIFIED to design, develop and deliver DNA and RNA testing for the medical management and identification of genomic and immune biomarkers in oncology.